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Crisaderm10 gm

Ointment

Crisaborole
ByIncepta Pharmaceuticals Ltd.
MRP ৳ 500.0010 % Off
Best PriceTk 450.00/10 gm tube
1
Section

Medicine overview

Indications of Crisaderm 10 gm

Crisaderm 10 gm is indicated for topical treatment of mild to moderate atopic dermatitis in pediatric patients 3 months of age and older.

Dosage of Crisaderm 10 gm

Apply a thin layer of Crisaderm 10 gm twice daily to affected areas. Crisaderm 10 gm is for topical use only and not for ophthalmic, oral, or intravaginal use.

Interaction of Crisaderm 10 gm

In vitro studies using human liver microsomes indicated that under the conditions of clinical use, Crisaderm 10 gm and metabolite 1 are not expected to inhibit cytochrome P450 (CYP) 1A2, 2B6, 2C8, 2C9, 2C19, 2D6, and 3A4. In vitro human liver microsomes studies for metabolite 2 showed that it did not inhibit activities of CYP2C19, 2D6, and 3A4.

Side Effects of Crisaderm 10 gm

Allergic reactions- Crisaderm 10 gm may cause allergic reactions at or near the application site. These can be serious and may include hives, itching, swelling, and redness. The most common side effect of Crisaderm 10 gm is application site pain, such as burning or stinging.

Precautions & Warnings

Hypersensitivity reactions, including contact urticaria have occurred in patients treated with Crisaderm 10 gm. If signs and symptoms of hypersensitivity occur, discontinue Crisaderm 10 gm immediately and initiate appropriate therapy.

Storage Conditions

Do not store above 30°C temperature. Keep away from light and out of the reach of children.

Drug Classes

Topical anti-inflammatory preparations

Mode Of Action

The active ingredient, Crisaderm 10 gm, is a phosphodiesterase-4 (PDE-4) inhibitor, mainly acting on phosphodiesterase 4B (PDE4B), which causes inflammation. Chemically, Crisaderm 10 gm is a phenoxybenzoxaborole. It contains a boron atom that helps penetrate the skin and is essential for its binding activity. Inhibition of PDE4B appears to suppress the release of tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines, proteins believed to be involved in the immune response and inflammation.

Pregnancy

Pregnancy: There is no available data with Crisaderm 10 gm in pregnant women to inform the drug-associated risk for major birth defects and miscarriage. In animal reproduction studies, there were no adverse developmental effects observed with oral administration of Crisaderm 10 gm in pregnant rats and rabbits during organogenesis at doses up to 3 and 2 times, respectively, the maximum recommended human dose (MRHD).Lactation: There is no information available on the presence of Crisaderm 10 gm in human milk. Crisaderm 10 gm is systemically absorbed. The lack of clinical data during lactation precludes a clear determination of the risk of Crisaderm 10 gm to a breastfed infant.

Frequently Asked Questions

What is Crisaderm 10 gm used for?

Crisaderm 10 gm is indicated for topical treatment of mild to moderate atopic dermatitis in pediatric patients 3 months of age and older.

What is the dosage of Crisaderm 10 gm?

Apply a thin layer of Crisaderm 10 gm twice daily to affected areas. Crisaderm 10 gm is for topical use only and not for ophthalmic, oral, or intravaginal use.

What are the side effects of Crisaderm 10 gm?

Allergic reactions- Crisaderm 10 gm may cause allergic reactions at or near the application site. These can be serious and may include hives, itching, swelling, and redness. The most common side effect of Crisaderm 10 gm is application site pain, such as burning or stinging.

What precautions should be taken with Crisaderm 10 gm?

Hypersensitivity reactions, including contact urticaria have occurred in patients treated with Crisaderm 10 gm. If signs and symptoms of hypersensitivity occur, discontinue Crisaderm 10 gm immediately and initiate appropriate therapy.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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