Hyalgun20 mg/ 2 ml

Hyalgun 20 mg/ 2 ml is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy, and to simple analgesics, e.g., acetaminophen.

Hyalgun 20 mg/ 2 ml is administered by intra-articular injection. A treatment cycle consists of five injections given at weekly intervals. Some patients may experience benefit with three injections given at weekly intervals. Inject the full 2 ml in one knee only. If treatment is bilateral, a separate injection should be used for each knee.

The common side-effects include gastrointestinal complaints, injection site pain, knee swelling/effusion, local skin reactions (rash, ecchymosis), pruritus, and headache.

The drug is contraindicated in patients with known hypersensitivity to hyaluronate preparations. Intra-articular injections are contraindicated in cases of past and present infections or skin diseases in the area of the injection site.

Use caution when injecting Hyalgun 20 mg/ 2 ml into patients who are allergic to avian proteins, feathers, and egg products. Strict aseptic administration technique must be followed. Remove joint effusion, if present, before injecting Hyalgun 20 mg/ 2 ml. Do not use the same syringe for removing joint effusion and for injecting Hyalgun 20 mg/ 2 ml. It is recommended that the patient avoid any stre…

The safety and effectiveness of Hyalgun 20 mg/ 2 ml have not been established in pregnant women. It is not known if Hyalgun 20 mg/ 2 ml is excreted in human milk. The safety and effectiveness of Hyalgun 20 mg/ 2 ml have not been established in lactating mother. The safety and effectiveness of Hyalgun 20 mg/ 2 ml have not been demonstrated in children.