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MB 121.5 mg

Tablet

Mecobalamin
ByACME Laboratories Ltd.
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Medicine overview

Indications of MB 12 1.5 mg

MB 12 1.5 mg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease ... Read moreMB 12 1.5 mg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease Diabetic retinopathy Entrapment neuropathy Drug induced neuropathy Megaloblastic anemia due to Vitamin B12 deficiency

Theropeutic Class

Drugs for Megaloblastic Anemia

Pharmacology

MB 12 1.5 mg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Dosage & Administration of MB 12 1.5 mg

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is  500 mcg MB 12 1.5 mg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.  Megaloblastic anemia: The usual adult dosage is  500 mcg MB 12 1.5 mg administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of MB 12 1.5 mg every one to three months as maintenance therapy

Dosage of MB 12 1.5 mg

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is  500 mcg MB 12 1.5 mg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.  Megaloblastic anemia: The usual adult dosage is  500 mcg MB 12 1.5 mg administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of MB 12 1.5 mg every one to three months as maintenance therapy

Interaction of MB 12 1.5 mg

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.

Contraindications

Hypersensitivity to any component of this product.

Side Effects of MB 12 1.5 mg

Generally MB 12 1.5 mg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of MB 12 1.5 mg.

Pregnancy & Lactation

Not recommended during pregnancy & lactation.

Precautions & Warnings

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Storage Conditions

Oral: Store at room temperature. Protect from moisture and light.Parenteral: Store at room temperature. Do not expose to direct light.

Use In Special Populations

Use in children: Not recommended.

Drug Classes

Drugs for Megaloblastic Anemia

Mode Of Action

MB 12 1.5 mg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Pregnancy

Not recommended during pregnancy & lactation.

Pediatric Uses

Use in children: Not recommended.

Frequently Asked Questions

What is MB 12 1.5 mg used for?

MB 12 1.5 mg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease ... Read moreMB 12 1.5 mg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkins…

What is the dosage of MB 12 1.5 mg?

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is 500 mcg MB 12 1.5 mg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms. …

What are the side effects of MB 12 1.5 mg?

Generally MB 12 1.5 mg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of MB 12 1.5 mg.

Who should not take MB 12 1.5 mg?

Hypersensitivity to any component of this product.

What precautions should be taken with MB 12 1.5 mg?

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Is MB 12 1.5 mg safe during pregnancy and breastfeeding?

Not recommended during pregnancy & lactation.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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