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Nepofer27.2 mg/5 ml

IV Infusion

Ferric Pyrophosphate Citrate
ByIncepta Pharmaceuticals Ltd.
MRP ৳ 500.005% Off
Best PriceTk 475.00/5 ml ampoule
1
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Medicine overview

Indications of Nepofer 27.2 mg/5 ml

Nepofer 27.2 mg/5 ml is indicated for the replacement of iron to maintain hemoglobin in adult patients with hemodialysis-dependent chronic kidney disease (HDD-CKD).

Theropeutic Class

Parenteral Iron Preparations

Dosage & Administration of Nepofer 27.2 mg/5 ml

Inspect Nepofer 27.2 mg/5 ml ampoule for signs of precipitation prior to mixing with the bicarbonate concentrate. Nepofer 27.2 mg/5 ml should only be added to the bicarbonate concentrate and should not be added to acid concentrate mixtures. Add Nepofer 27.2 mg/5 ml to bicarbonate concentrate used for generation of hemodialysate. The final concentration of iron (III) in the final hemodialysate is 2 micromolar (110 mcg/L). Multiple ampoules can be added to the master bicarbonate mix at each center at a ratio of one ampoule to each 2.5 gallons of bicarbonate concentrate.Administer Nepofer 27.2 mg/5 ml to patients at each dialysis procedure for as long as patients are receiving maintenance hemodialysis therapy for CKD.Hemodialysis solutions should be used within 24 hours of the preparation of the Nepofer 27.2 mg/5 ml /bicarbonate concentrate mixture.

Dosage of Nepofer 27.2 mg/5 ml

Inspect Nepofer 27.2 mg/5 ml ampoule for signs of precipitation prior to mixing with the bicarbonate concentrate. Nepofer 27.2 mg/5 ml should only be added to the bicarbonate concentrate and should not be added to acid concentrate mixtures. Add Nepofer 27.2 mg/5 ml to bicarbonate concentrate used for generation of hemodialysate. The final concentration of iron (III) in the final hemodialysate is 2 micromolar (110 mcg/L). Multiple ampoules can be added to the master bicarbonate mix at each center at a ratio of one ampoule to each 2.5 gallons of bicarbonate concentrate.Administer Nepofer 27.2 mg/5 ml to patients at each dialysis procedure for as long as patients are receiving maintenance hemodialysis therapy for CKD.Hemodialysis solutions should be used within 24 hours of the preparation of the Nepofer 27.2 mg/5 ml /bicarbonate concentrate mixture.

Interaction of Nepofer 27.2 mg/5 ml

Formal drug interaction studies have not been performed for Nepofer 27.2 mg/5 ml.

Side Effects of Nepofer 27.2 mg/5 ml

The most common side effects are headache, peripheral edema, asthenia, AV fistula thrombosis, urinary tract infection, AV fistula site hemorrhage, pyrexia, fatigue, hypotension, muscle spasms, pain in extremity, back pain, and dyspnea.

Pregnancy & Lactation

Pregnant women Category C. Lactating mothers It is not known whether Nepofer 27.2 mg/5 ml is present in human milk or not.

Precautions & Warnings

Hypersensitivity Reactions: Anaphylactic-type reactions, shock, hypotension, loss of consciousness and collapse can occur. Monitor patients for signs and symptoms of hypersensitivity during and after hemodialysis until he/she is clinically stable. Personnel and therapies should be immediately available for the treatment of serious hypersensitivity reactions.Iron laboratory testing: Iron status should be determined on pre-dialysis blood samples. Post dialysis serum iron parameters may overestimate serum iron and transferrin saturation.

Overdose Effects of Nepofer 27.2 mg/5 ml

No data are available regarding overdose of Nepofer 27.2 mg/5 ml.

Storage Conditions

Keep in a cool and dry place, away from light. Keep out of reach of children.

Drug Classes

Parenteral Iron Preparations

Pregnancy

Pregnant women Category C. Lactating mothers It is not known whether Nepofer 27.2 mg/5 ml is present in human milk or not.

Frequently Asked Questions

What is Nepofer 27.2 mg/5 ml used for?

Nepofer 27.2 mg/5 ml is indicated for the replacement of iron to maintain hemoglobin in adult patients with hemodialysis-dependent chronic kidney disease (HDD-CKD).

What is the dosage of Nepofer 27.2 mg/5 ml?

Inspect Nepofer 27.2 mg/5 ml ampoule for signs of precipitation prior to mixing with the bicarbonate concentrate. Nepofer 27.2 mg/5 ml should only be added to the bicarbonate concentrate and should not be added to acid concentrate mixtures. Add Nepofer 27.2 mg/5 ml to bicarbonate concentrate used for generation of hemodialysate. The final concentration of iron (III) in the final hemodialysate is 2…

What are the side effects of Nepofer 27.2 mg/5 ml?

The most common side effects are headache, peripheral edema, asthenia, AV fistula thrombosis, urinary tract infection, AV fistula site hemorrhage, pyrexia, fatigue, hypotension, muscle spasms, pain in extremity, back pain, and dyspnea.

What precautions should be taken with Nepofer 27.2 mg/5 ml?

Hypersensitivity Reactions: Anaphylactic-type reactions, shock, hypotension, loss of consciousness and collapse can occur. Monitor patients for signs and symptoms of hypersensitivity during and after hemodialysis until he/she is clinically stable. Personnel and therapies should be immediately available for the treatment of serious hypersensitivity reactions.Iron laboratory testing: Iron status sho…

Is Nepofer 27.2 mg/5 ml safe during pregnancy and breastfeeding?

Pregnant women Category C. Lactating mothers It is not known whether Nepofer 27.2 mg/5 ml is present in human milk or not.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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