Orthogen

Orthogen is indicated for the management and support of joint health, cartilage function, and mobility, especially in degenerative and inflammatory joint conditions.

It is commonly used for:

• Osteoarthritis (knee, hip, and spine) to reduce joint pain, stiffness, and inflammation
• Age-related joint degeneration and cartilage wear
• Joint discomfort and reduced mobility due to wear-and-tear conditions
• Support for cartilage repair and maintenance of joint structure
• Inflammatory joint conditions associated with stiffness and swelling
• Improvement of joint flexibility and physical function in active and elderly individuals

This multi-nutrient formulation supports cartilage integrity, anti-inflammatory action, and joint lubrication, helping improve overall joint comfort and mobility.

Orthogen contains a scientifically balanced combination of cartilage-supporting, anti-inflammatory, and bone-supporting nutrients to promote joint function and mobility.

Each tablet contains:

• Undenatured Type II Collagen – 20 mg
• Glucosamine Sulfate – 750 mg
• Boswellia serrata extract – 50 mg
• Boron (as Calcium Fructoborate) – 0.75 mg

Orthogen supports cartilage regeneration, synovial joint lubrication, and inflammatory balance, helping maintain healthy joints and improved mobility in degenerative joint conditions.

Orthogen generally has a low risk of clinically significant drug interactions, but caution is advised with certain medications, particularly anticoagulants.

With medicines:

• Anticoagulants (blood thinners) such as warfarin, heparin, and other anticoagulant therapies: May increase the risk of bleeding when used concomitantly with Glucosamine sulfate and Boswellia serrata. Careful monitoring is recommended.
• Other medications: No significant clinically relevant interactions have been widely reported with Undenatured Type II Collagen or Boron.

Orthogen is generally well tolerated, but some individuals may experience mild and temporary adverse effects, mainly related to gastrointestinal sensitivity.

Common side effects include:

• Nausea or mild gastric discomfort
• Heartburn or acid reflux
• Diarrhea or constipation

Less common side effects include:

• Headache
• Drowsiness or fatigue
• Mild skin reactions (rash or itching)

Rare considerations:

• Variability in product quality may lead to differences in active ingredient content, though this is formulation-dependent and not a direct pharmacological effect.

General advice:
Most side effects are mild and resolve with continued use or dose adjustment. If symptoms persist or worsen, medical consultation is recommended.

Not recommended duration pregnancy and lactation.

Orthogen should be used with caution in patients with underlying metabolic, renal, or hepatic conditions, and regular monitoring may be required.

Key precautions include:

• Diabetes mellitus: Patients should regularly monitor blood glucose levels, as Glucosamine sulfate may potentially affect insulin sensitivity.
• Renal impairment: Limited clinical data are available in patients with kidney dysfunction; use in severe renal impairment should be done under medical supervision.
• Hepatic impairment: Safety data in liver disease are limited; caution is advised in patients with moderate to severe hepatic insufficiency.
• Medical supervision: Long-term use should be guided by a healthcare professional, especially in patients with chronic metabolic or organ-related disorders.

General warning:
Patients with significant renal, hepatic, or metabolic conditions should use Orthogen only under appropriate medical supervision to ensure safety and effective monitoring.

Data on overdose of Orthogen is limited; however, excessive intake may lead to mainly gastrointestinal-related symptoms.

Possible overdose effects include:

• Nausea and vomiting
• Diarrhea or constipation
• Abdominal discomfort or bloating

General advice:
In case of suspected overdose, symptomatic and supportive care is recommended. Patients should discontinue use and seek medical advice if significant or persistent symptoms occur. Adherence to the prescribed dose helps minimize the risk of adverse effects.

Store below 30° C temperature & in dry place, protected from light. Keep out of the reach of children.