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Medicine overview

Indications of Pedial 500 mcg

Pedial 500 mcg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease ... Read morePedial 500 mcg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease Diabetic retinopathy Entrapment neuropathy Drug induced neuropathy Megaloblastic anemia due to Vitamin B12 deficiency

Theropeutic Class

Drugs for Megaloblastic Anemia

Pharmacology

Pedial 500 mcg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Dosage & Administration of Pedial 500 mcg

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is  500 mcg Pedial 500 mcg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.  Megaloblastic anemia: The usual adult dosage is  500 mcg Pedial 500 mcg administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Pedial 500 mcg every one to three months as maintenance therapy

Dosage of Pedial 500 mcg

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is  500 mcg Pedial 500 mcg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.  Megaloblastic anemia: The usual adult dosage is  500 mcg Pedial 500 mcg administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Pedial 500 mcg every one to three months as maintenance therapy

Interaction of Pedial 500 mcg

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.

Contraindications

Hypersensitivity to any component of this product.

Side Effects of Pedial 500 mcg

Generally Pedial 500 mcg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Pedial 500 mcg.

Pregnancy & Lactation

Not recommended during pregnancy & lactation.

Precautions & Warnings

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Storage Conditions

Oral: Store at room temperature. Protect from moisture and light.Parenteral: Store at room temperature. Do not expose to direct light.

Use In Special Populations

Use in children: Not recommended.

Drug Classes

Drugs for Megaloblastic Anemia

Mode Of Action

Pedial 500 mcg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Pregnancy

Not recommended during pregnancy & lactation.

Pediatric Uses

Use in children: Not recommended.

Frequently Asked Questions

What is Pedial 500 mcg used for?

Pedial 500 mcg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease ... Read morePedial 500 mcg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Par…

What is the dosage of Pedial 500 mcg?

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is 500 mcg Pedial 500 mcg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms…

What are the side effects of Pedial 500 mcg?

Generally Pedial 500 mcg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Pedial 500 mcg.

Who should not take Pedial 500 mcg?

Hypersensitivity to any component of this product.

What precautions should be taken with Pedial 500 mcg?

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Is Pedial 500 mcg safe during pregnancy and breastfeeding?

Not recommended during pregnancy & lactation.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.