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Receca100 mg
NIPRO JMI Pharma Ltd.
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Medicine overview
Indications of Rehydril 100 mg
Rehydril 100 mg is indicated for the symptomatic treatment of acute diarrhea.
Theropeutic Class
Anti-diarrhoeal
Pharmacology
Rehydril 100 mg increases the availability of endogenous opioids (enkephalins) by inhibiting the membrane-bound enkephalinase. The enkephalins in turn mediate their effect through δ receptor ( delta opioid receptor) activation that induces a selective increase in Cl absorption by inhibiting adenylate cyclase.Onset: 30 min (plasma enkephalinase inhibition).
Dosage & Administration of Rehydril 100 mg
Adults: One capsule initially, regardless of the time of day. Then one capsule three times daily preferably before the main meals. Children (from 3 months of age): Rehydril 100 mg granules should be administered together with oral rehydration. The recommended dose is determined according to body weight: 1.5 mg/kg per administration, three times daily.
Infants less than 9 kg: one 10 mg sachet 3 times daily.
Infants from 9 kg to 13 kg: two 10 mg sachets 3 times daily.
Children from 13 kg to 27 kg: one 30mg sachet 3 times daily.
Children of more than 27 kg: two 30mg sachets 3 times daily.
Dosage of Rehydril 100 mg
Adults: One capsule initially, regardless of the time of day. Then one capsule three times daily preferably before the main meals. Children (from 3 months of age): Rehydril 100 mg granules should be administered together with oral rehydration. The recommended dose is determined according to body weight: 1.5 mg/kg per administration, three times daily.
Infants less than 9 kg: one 10 mg sachet 3 times daily.
Infants from 9 kg to 13 kg: two 10 mg sachets 3 times daily.
Children from 13 kg to 27 kg: one 30mg sachet 3 times daily.
Children of more than 27 kg: two 30mg sachets 3 times daily.
Interaction of Rehydril 100 mg
No drug interactions found. Joint treatment with Rehydril 100 mg and Loperamide or Nifuroxazide does not modify the kinetics of Rehydril 100 mg.
Contraindications
Hypersensitivity to Rehydril 100 mg, or to any of the excipients.
Side Effects of Rehydril 100 mg
Headache, erythema multiforme, urticaria, angioedema may be seen.
Pregnancy & Lactation
Due to a lack of clinical data, Rehydril 100 mg should not be administered to pregnant or breastfeeding women.
Precautions & Warnings
The administration of Rehydril 100 mg does not modify the usual rehydration regimens. The presence of bloody stools and fever may indicate the presence of invasive bacteria as a reason for diarrhea or the presence of other severe disease. Rehydril 100 mg has not been tested in antibiotic-associated diarrhea and should therefore not be administered under these conditions. Caution should be taken in patients with renal or liver impairment.
Overdose Effects of Rehydril 100 mg
No cases of overdose have been reported. In adults, single doses above 2 g which is equivalent to 20 times the therapeutic dose, have been administered, and no harmful effects have been described.
Drug Classes
Anti-diarrhoeal
Mode Of Action
Rehydril 100 mg increases the availability of endogenous opioids (enkephalins) by inhibiting the membrane-bound enkephalinase. The enkephalins in turn mediate their effect through δ receptor ( delta opioid receptor) activation that induces a selective increase in Cl absorption by inhibiting adenylate cyclase.Onset: 30 min (plasma enkephalinase inhibition).
Pregnancy
Due to a lack of clinical data, Rehydril 100 mg should not be administered to pregnant or breastfeeding women.
Frequently Asked Questions
What is Rehydril 100 mg used for?
Rehydril 100 mg is indicated for the symptomatic treatment of acute diarrhea.
What is the dosage of Rehydril 100 mg?
Adults: One capsule initially, regardless of the time of day. Then one capsule three times daily preferably before the main meals. Children (from 3 months of age): Rehydril 100 mg granules should be administered together with oral rehydration. The recommended dose is determined according to body weight: 1.5 mg/kg per administration, three times daily. Infants less than 9 kg: one 10 mg sachet 3 tim…
What are the side effects of Rehydril 100 mg?
Headache, erythema multiforme, urticaria, angioedema may be seen.
Who should not take Rehydril 100 mg?
Hypersensitivity to Rehydril 100 mg, or to any of the excipients.
What precautions should be taken with Rehydril 100 mg?
The administration of Rehydril 100 mg does not modify the usual rehydration regimens. The presence of bloody stools and fever may indicate the presence of invasive bacteria as a reason for diarrhea or the presence of other severe disease. Rehydril 100 mg has not been tested in antibiotic-associated diarrhea and should therefore not be administered under these conditions. Caution should be taken in…
Is Rehydril 100 mg safe during pregnancy and breastfeeding?
Due to a lack of clinical data, Rehydril 100 mg should not be administered to pregnant or breastfeeding women.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.