10% Off
Crisaderm10 gm
Incepta Pharmaceuticals Ltd.
৳450.00
Add to cart
Best PriceTk 450.00/10 gm tube
Out Of Stock1
Alternatives
Price
Medicine overview
Indications of Crisa 10 gm
Crisa 10 gm is indicated for topical treatment of mild to moderate atopic dermatitis in pediatric patients 3 months of age and older.
Dosage of Crisa 10 gm
Apply a thin layer of Crisa 10 gm twice daily to affected areas. Crisa 10 gm is for topical use only and not for ophthalmic, oral, or intravaginal use.
Interaction of Crisa 10 gm
In vitro studies using human liver microsomes indicated that under the conditions of clinical use, Crisa 10 gm and metabolite 1 are not expected to inhibit cytochrome P450 (CYP) 1A2, 2B6, 2C8, 2C9, 2C19, 2D6, and 3A4. In vitro human liver microsomes studies for metabolite 2 showed that it did not inhibit activities of CYP2C19, 2D6, and 3A4.
Side Effects of Crisa 10 gm
Allergic reactions- Crisa 10 gm may cause allergic reactions at or near the application site. These can be serious and may include hives, itching, swelling, and redness. The most common side effect of Crisa 10 gm is application site pain, such as burning or stinging.
Precautions & Warnings
Hypersensitivity reactions, including contact urticaria have occurred in patients treated with Crisa 10 gm. If signs and symptoms of hypersensitivity occur, discontinue Crisa 10 gm immediately and initiate appropriate therapy.
Storage Conditions
Do not store above 30°C temperature. Keep away from light and out of the reach of children.
Drug Classes
Topical anti-inflammatory preparations
Mode Of Action
The active ingredient, Crisa 10 gm, is a phosphodiesterase-4 (PDE-4) inhibitor, mainly acting on phosphodiesterase 4B (PDE4B), which causes inflammation. Chemically, Crisa 10 gm is a phenoxybenzoxaborole. It contains a boron atom that helps penetrate the skin and is essential for its binding activity. Inhibition of PDE4B appears to suppress the release of tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines, proteins believed to be involved in the immune response and inflammation.
Pregnancy
Pregnancy: There is no available data with Crisa 10 gm in pregnant women to inform the drug-associated risk for major birth defects and miscarriage. In animal reproduction studies, there were no adverse developmental effects observed with oral administration of Crisa 10 gm in pregnant rats and rabbits during organogenesis at doses up to 3 and 2 times, respectively, the maximum recommended human dose (MRHD).Lactation: There is no information available on the presence of Crisa 10 gm in human milk. Crisa 10 gm is systemically absorbed. The lack of clinical data during lactation precludes a clear determination of the risk of Crisa 10 gm to a breastfed infant.
Frequently Asked Questions
What is Crisa 10 gm used for?
Crisa 10 gm is indicated for topical treatment of mild to moderate atopic dermatitis in pediatric patients 3 months of age and older.
What is the dosage of Crisa 10 gm?
Apply a thin layer of Crisa 10 gm twice daily to affected areas. Crisa 10 gm is for topical use only and not for ophthalmic, oral, or intravaginal use.
What are the side effects of Crisa 10 gm?
Allergic reactions- Crisa 10 gm may cause allergic reactions at or near the application site. These can be serious and may include hives, itching, swelling, and redness. The most common side effect of Crisa 10 gm is application site pain, such as burning or stinging.
What precautions should be taken with Crisa 10 gm?
Hypersensitivity reactions, including contact urticaria have occurred in patients treated with Crisa 10 gm. If signs and symptoms of hypersensitivity occur, discontinue Crisa 10 gm immediately and initiate appropriate therapy.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.